@article{AOE4765,
author = {Qiuping Wang and Rhianna K. Lenham and Xiu Wang and Yifei Li and Manjie Jiang and Wei Chen and Li Xu and Changqing Yang and Andrew D. Woodcock and Peter W. Dettmar},
title = {A pilot study demonstrating the evidence for reflux disease in patients presenting with non-allergic rhinitis (NAR)—reflux disease in association with non-allergic rhinitis},
journal = {Annals of Esophagus},
volume = {2},
number = {0},
year = {2019},
keywords = {},
abstract = {Background: To overcome the misdiagnosis of reflux disease and provide subjects with the appropriate treatment determine the link between non-allergic rhinitis (NAR) and reflux disease through analyzing pepsin concentration in patients presenting with NAR using the reflux diagnostic test, Peptest.
Methods: Patients with negative allergen skin prick tests and CT scans of the sinuses were recruited from ENT outpatient visits. All patients provided an eosinophil count and underwent nasal endoscopy with all participants completing the Reflux Disease Questionnaire. Participants (31 patients and 42 healthy) provided one postprandial saliva sample and patients with NAR provided nasal lavage and additional saliva on waking and post-symptom for the determination of pepsin concentration by Peptest. Pepsin concentrations >25 ng/mL were considered positive and eosinophil counts },
issn = {2616-2784}, url = {https://aoe.amegroups.org/article/view/4765}
}