@article{AOE4604,
author = {Luciana C. Silva and Fernando A. M. Herbella},
title = {The effect of oral sucralfate on postprandial proximal gastric acid pocket},
journal = {Annals of Esophagus},
volume = {1},
number = {0},
year = {2018},
keywords = {},
abstract = {Background: A postprandial proximal gastric acidpocket (PPGAP) that escapes neutralization by food was demonstrated involunteers and gastroesophageal reflux disease (GERD) patients. It is elusive;however, if this acid layer is morphologically best conceptualized as a realpocket or a film. This study aims to analyze the effect of oral sucralfateadministration on PPGAP to shed some light on PPGAP morphology and treatment.
Methods: Twenty-six patients (mean age 51years, 19 females) were studied. A pull-through pH monitoring was performedfrom 5 cm below the lower border of the lower esophageal sphincter (LES) to theactual border in increments of 1 cm, in a fasting state, 10 min after a fattymeal and 10 min after oral sucralfate administration. PPGAP was defined by anacid reading (pH },
issn = {2616-2784}, url = {https://aoe.amegroups.org/article/view/4604}
}